Abstract / Excerpt:

This study aims to determine the effect of two widely known food supplements on the market on the cholesterol levels of Mus Muculus. For the experiment, twenty male Mus Muculus about two to three months old were used and divided into four groups namely the control group, the capsule A group, the capsule B group and the Rosuvastatin group. Each group has five replicates all randomly selected. Food and water were given to the mice. An experimental period was allotted for the acclimatization. Blood cholesterol level induction was applied to induce hypercholesterolemia to the test subjects. After every experimental stage, acclimatization, induction, and treatment, blood samples were taken from the mice using the submandibular vein blood sampling for mice method. The blood cholesterol levels were obtained through laboratory analysis. Initial results showed a decrease in blood cholesterol level in both experimental and Rosuvastatin treatments. Raw data of the blood cholesterol levels were then subjected to three statistical tools: the Kruskal-Wallis and Median test, the Mann-Whitney test and finally, the Wilcoxon paired test. The results of the statistical analyses proved that the blood cholesterol level of the Mus musculus was not significantly reduced by capsule A or capsule B. Capsule A was slightly more potent in its anti-cholesterolic effect compared to capsule B. Further experimentation would require the use different concentrations of the treatments and consider proper feeding schedules to maximize the effect of the treatment.

Info

Source Institution	Ateneo de Davao University
Unit	Natural Science and Mathematics
Authors	Butiong, Gerwin Emmanuel V., Corbeta, March Kyle Joshua T., Leonar, Patrick D.
Page Count	45
Place of Publication	Davao City
Original Publication Date	March 1, 2014
Tags	Biology, Food Supplements, Research

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